Clinical application of CRISPR-Cas9 technology for large deletions of somatic mutations is inefficient, and methods to improve utility suffer from our inability to rapidly assess mono- vs.biallelic deletions.Here we establish a model system for investigating allelic heterogeneity at the single-cell level and identify indel scarring from non-simulta
In some cases of Intensity-modulated radiotherapy (IMRT) point dose measurement, there exists significant deviation between calculated and measured dose at Black Tea isocenter, sometimes greater than ±3%.This may be because IMRT fields generate complex profiles at the reference point.The deviation arises due to lack of lateral electro
To date, a sufficient volume of clinical studies has been accumulated that have demonstrated a reduced antiplatelet effect of enteric-coated (EC) lowdose acetylsalicylic acid (ASA).Delayed and incomplete absorption from the intestinal alkaline medium, which significantly reduces the bioavailability of drug, is considered the main reason for laborat
There is experimentally demonstrated sensitivity of the magnetic noise methods to the change of the structure of cast iron articles KCh 30-6 surface coating with an example of radiator nipple.As a result of measuring there AC Power Switch Set is disclosed the increase Cooktop Knob of magnetic noise in case of presence of decarbonized lay on the sur
Fuzzy C-Means is a clustering algorithm widely used in many applications.However, its computational complexity is very large, which prevents its use for large problem instances.Therefore, a hybrid improvement is proposed for the algorithm, which considerably reduces the number of iterations and, in many cases, improves the solution quality, Cooktop